CKMT1A anticorps (AA 258-417)

N° du produit ABIN1679244

Cet anticorps anti-CKMT1A est un anticorps Lapin Polyclonal détectant CKMT1A dans WB. Adapté pour Humain.

Aperçu rapide pour CKMT1A anticorps (AA 258-417) (ABIN1679244)

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CKMT1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CKMT1A anticorps

Épitope: AA 258-417

Séquence: FLIWVNEEDH TRVISMEKGG NMKRVFERFC RGLKEVERLI QERGWEFMWN ERLGYILTCP SNLGTGLRAG VHIKLPLLSK DSRFPKILEN LRLQKRGTGG VDTAATGGVF DISNLDRLGK SEVELVQLVI DGVNYLIDCE RRLERGQDIR IPTPVIHTKH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 258-417 of human CKMT1A (NP_001015001.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CKMT1A

Antigène: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Autre désignation: CKMT1A

Sujet: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.,CKMT1A,CKMT1,U-MtCK,mia-CK,Signal Transduction,Kinase,CKMT1A

Poids moléculaire: 47 kDa/50 kDa

ID gène: 548596

UniProt: P12532