DRG1 anticorps (AA 158-367)
Aperçu rapide pour DRG1 anticorps (AA 158-367) (ABIN1679602)
Antigène
Voir toutes DRG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 158-367
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Séquence
- KKIIENELEG FGIRLNSKPP NIGFKKKDKG GINLTATCPQ SELDAETVKS ILAEYKIHNA DVTLRSDATA DDLIDVVEGN RVYIPCIYVL NKIDQISIEE LDIIYKVPHC VPISAHHRWN FDDLLEKIWD YLKLVRIYTK PKGQLPDYTS PVVLPYSRTT VEDFCMKIHK NLIKEFKYAL VWGLSVKHNP QKVGKDHTLE DEDVIQIVKK
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human DRG1 (NP_004138.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DRG1 (Developmentally Regulated GTP Binding Protein 1 (DRG1))
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Autre désignation
- DRG1
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Sujet
- Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these microtubule-related functions.,DRG1,NEDD3,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,DRG1
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Poids moléculaire
- 40 kDa
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ID gène
- 4733
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UniProt
- Q9Y295
Antigène
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