GTPBP4 anticorps (AA 385-634)

N° du produit ABIN1680142

Cet anticorps Lapin Polyclonal détecte spécifiquement GTPBP4 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour GTPBP4 anticorps (AA 385-634) (ABIN1680142)

Antigène: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTPBP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-GTPBP4 anticorps

Épitope: AA 385-634

Séquence: RKRMETEESR KKRERDLELE MGDDYILDLQ KYWDLMNLSE KHDKIPEIWE GHNIADYIDP AIMKKLEELE KEEELRTAAG EYDSVSESED EEMLEIRQLA KQIREKKKLK ILESKEKNTQ GPRMPRTAKK VQRTVLEKEM RSLGVDMDDK DDAHYAVQAR RSRSITRKRK REDSAPPSSV ARSGSCSRTP RDVSGLRDVK MVKKAKTMMK NAQKKMNRLG KKGEADRHVF DMKPKHLLSG KRKAGKKDRR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 385-634 of human GTPBP4 (NP_036473.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GTPBP4

Antigène: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Autre désignation: GTPBP4

Sujet: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.,GTPBP4,CRFG,NGB,NOG1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor suppressors,Signal Transduction,GTPBP4

Poids moléculaire: 60 kDa/68 kDa/73 kDa

ID gène: 23560

UniProt: Q9BZE4