IVNS1ABP anticorps (AA 1-300)
Aperçu rapide pour IVNS1ABP anticorps (AA 1-300) (ABIN1680538)
Antigène
Voir toutes IVNS1ABP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-300
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Séquence
- MIPNGYLMFE DENFIESSVA KLNALRKSGQ FCDVRLQVCG HEMLAHRAVL ACCSPYLFEI FNSDSDPHGI SHVKFDDLNP EAVEVLLNYA YTAQLKADKE LVKDVYSAAK KLKMDRVKQV CGDYLLSRMD VTSCISYRNF ASCMGDSRLL NKVDAYIQEH LLQISEEEEF LKLPRLKLEV MLEDNVCLPS NGKLYTKVIN WVQRSIWENG DSLEELMEEV QTLYYSADHK LLDGNLLDGQ AEVFGSDDDH IQFVQKKPPR ENGHKQISSS STGCLSSPNA TVQSPKHEWK IVASEKTSNN
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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Autre désignation
- IVNS1ABP
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Classe de substances
- Influenza Protein
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Sujet
- Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats (By similarity. Protects cells from cell death induced by actin destabilization (By similarity. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20 E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro.,IVNS1ABP,FLARA3,HSPC068,KLHL39,ND1,NS-1,NS1-BP,NS1BP,IVNS1ABP
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Poids moléculaire
- 71 kDa
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ID gène
- 10625
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UniProt
- Q9Y6Y0
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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