MYCN anticorps (AA 168-267)

N° du produit ABIN1680957

Cité dans 1 publication. Cet anticorps anti-MYCN Polyclonal Lapin (ABIN1680957) détecte spécifiquement MYCN dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MYCN anticorps (AA 168-267) (ABIN1680957)

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYCN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MYCN anticorps

Épitope: AA 168-267

Séquence: AGRAGAALPA ELAHPAAECV DPAVVFPFPV NKREPAPVPA APASAPAAGP AVASGAGIAA PAGAPGVAPP RPGGRQTSGG DHKALSTSGE DTLSDSDDED

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 168-267 of human MYCN (NP_005369.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-MYCN (ABIN1680957)

Chang, Yang, Zheng, Li, Nie: "Arsenic trioxide inhibits cancer stem-like cells via down-regulation of Gli1 in lung cancer." dans: American journal of translational research, Vol. 8, Issue 2, pp. 1133-43, (2016) (PubMed).

Détails sur MYCN

Antigène: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Autre désignation: MYCN

Sujet: This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,MODED,N-myc,NMYC,ODED,bHLHe37,MYCN,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,MYCN

Poids moléculaire: 49 kDa

ID gène: 4613

UniProt: P04198