NBR1 anticorps
Aperçu rapide pour NBR1 anticorps (ABIN1680974)
Antigène
Voir toutes NBR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain, Singe, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant protein of human NBR1
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:100,IP,1:20 - 1:50
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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Autre désignation
- NBR1
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Sujet
- The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.,NBR1,1A1-3B,IAI3B,M17S2,MIG19,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial Control of Autophagy,NBR1
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Poids moléculaire
- 103 kDa/107 kDa
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ID gène
- 4077
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UniProt
- Q14596
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Pathways
- Autophagy
Antigène
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