NUMA1 anticorps (AA 1-309)
Aperçu rapide pour NUMA1 anticorps (AA 1-309) (ABIN1681136)
Antigène
Voir toutes NUMA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-309
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Séquence
- MTLHATRGAA LLSWVNSLHV ADPVEAVLQL QDCSIFIKII DRIHGTEEGQ QILKQPVSER LDFVCSFLQK NRKHPSSPEC LVSAQKVLEG SELELAKMTM LLLYHSTMSS KSPRDWEQFE YKIQAELAVI LKFVLDHEDG LNLNEDLENF LQKAPVPSTC SSTFPEELSP PSHQAKREIR FLELQKVASS SSGNNFLSGS PASPMGDILQ TPQFQMRRLK KQLADERSNR DELELELAEN RKLLTEKDAQ IAMMQQRIDR LALLNEKQAA SPLEPKELEE LRDKNESLTM RLHETLKQCQ DLKTEKSQM
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human NUMA1 (NP_006176.2).
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Isotype
- IgG
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Indications d'application
- WB,1:200 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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Autre désignation
- NUMA1
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Sujet
- This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.,NUMA1,NMP-22,NUMA,Cell Biology & Developmental Biology,Cell Cycle,NUMA1
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Poids moléculaire
- 109 kDa/200 kDa/201 kDa/236 kDa/238 kDa
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ID gène
- 4926
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UniProt
- Q14980
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Pathways
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
Antigène
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