PLAA anticorps (AA 536-795)

N° du produit ABIN1682194

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAA dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PLAA anticorps (AA 536-795) (ABIN1682194)

Antigène: PLAA (Phospholipase A2-Activating Protein (PLAA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLAA anticorps

Épitope: AA 536-795

Séquence: PKKEAVTFDQ ANPTQILGKL KELNGTAPEE KKLTEDDLIL LEKILSLICN SSSEKPTVQQ LQILWKAINC PEDIVFPALD ILRLSIKHPS VNENFCNEKE GAQFSSHLIN LLNPKGKPAN QLLALRTFCN CFVGQAGQKL MMSQRESLMS HAIELKSGSN KNIHIALATL ALNYSVCFHK DHNIEGKAQC LSLISTILEV VQDLEATFRL LVALGTLISD DSNAVQLAKS LGVDSQIKKY SSVSEPAKVS ECCRFILNLL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 536-795 of human PLAA (NP_001026859.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAA

Antigène: PLAA (Phospholipase A2-Activating Protein (PLAA))

Autre désignation: PLAA

Sujet: Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling (By similarity. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development (By similarity. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha- or lipopolysaccharide (LPS-dependent manner, and hence prostaglandin E2 biosynthesis.,PLAA,DOA1,PLA2P,PLAP,NDMSBA,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,PLAA

Poids moléculaire: 87 kDa

ID gène: 9373

UniProt: Q9Y263