SNAIL anticorps (AA 1-100)

N° du produit ABIN1682836

Cet anticorps Lapin Polyclonal détecte spécifiquement SNAIL dans WB, IHC et IF. Il présente une réactivité envers Humain et a été mentionné dans 6+ publications.

Aperçu rapide pour SNAIL anticorps (AA 1-100) (ABIN1682836)

Antigène: SNAIL (SNAI1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAIL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SNAIL anticorps

Épitope: AA 1-100

Séquence: MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL NPTASLPMLI WDSVLAPQAQ PIAWASLRLQ ESPRVAELTS LSDEDSGKGS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Snail (NP_005976.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-SNAIL (ABIN1682836)

Yang, Qiu, Xiao, Hu, Liu, Chen, Huang, Li, Li, Zhang, Ding, Xiang: "AP-2β inhibits hepatocellular carcinoma invasion and metastasis through Slug and Snail to suppress epithelial-mesenchymal transition." dans: Theranostics, Vol. 8, Issue 13, pp. 3707-3721, (2018) (PubMed).

Wang, Dong, Wang, Li, Dong, Jeyalatha, Wu, Shen, Yang, Chen, Xue, Liu, Li: "Epithelial dysplasia in pterygium postoperative granuloma." dans: Experimental eye research, Vol. 175, pp. 199-206, (2018) (PubMed).

Du, Fang, Chen, Teng, Xiao, Xie, Jin, Wang: "Effect of silencing the T‑Box transcription factor TBX2 in prostate cancer PC3 and LNCaP cells." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 6050-6058, (2018) (PubMed).

Zhan, Chen, Chen: "Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF-β induced EMT in pancreatic cancer cells." dans: Oncology letters, Vol. 16, Issue 1, pp. 924-930, (2018) (PubMed).

Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

Xu, Zhu, Zhao, Chen, Zhang, Yuan, Deng, Dou, Wang, Huang, Chen, Jiang, Yu: "Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors." dans: Oncotarget, Vol. 6, Issue 2, pp. 979-94, (2015) (PubMed).

Détails sur SNAIL

Antigène: SNAIL (SNAI1)

Autre désignation: SNAI1

Sujet: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.,SNAI1,SLUGH2,SNA,SNAH,SNAIL,SNAIL1,dJ710H13.1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cardiovascular,Heart,Cardiogenesis,SNAI1

Poids moléculaire: 29 kDa

ID gène: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling