TAF9 anticorps (AA 1-172)
Aperçu rapide pour TAF9 anticorps (AA 1-172) (ABIN1682962)
Antigène
Voir toutes TAF9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-172
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Séquence
- MLLPNILLTG TPGVGKTTLG KELASKSGLK YINVGDLARE EQLYDGYDEE YDCPILDEDR VVDELDNQMR EGGVIVDYHG CDFFPERWFH IVFVLRTDTN VLYERLETRG YNEKKLTDNI QCEIFQVLYE EATASYKEEI VHQLPSNKPE ELENNVDQIL KWIEQWIKDH NS
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Réactivité croisée
- Humain, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TAF9 (NP_057367.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TAF9 (RNA Polymerase II TBP-Associated Factor Subunit G (TAF9))
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Autre désignation
- TAF9
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Sujet
- Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. In human, TAF9 and AK6 (GeneID: 102157402) are two distinct genes that share 5' exons. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants.,TAF9,MGC:5067,STAF31/32,TAF2G,TAFII-31,TAFII-32,TAFII31,TAFII32,TAFIID32,Epigenetics & Nuclear Signaling,TAF9
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Poids moléculaire
- 28 kDa
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ID gène
- 6880
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UniProt
- Q16594
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Antigène
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