TRIOBP anticorps (AA 180-310)
Aperçu rapide pour TRIOBP anticorps (AA 180-310) (ABIN1683149)
Antigène
Voir toutes TRIOBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 180-310
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Séquence
- DVTKLSDSNK ENALHSYSTQ KGPLKAGEQR AGSEVISRGG PRKADGQRQA LDYVELSPLT QASPQRARTP ARTPDRLAKQ EELERDLAQR SEERRKWFEA TDSRTPEVPA GEGPRRGLGA PLTEDQQNRL S
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 180-310 of human TRIOBP (NP_008963.3).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))
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Autre désignation
- TRIOBP
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Sujet
- This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).,TRIOBP,DFNB28,HRIHFB2122,TAP68,TARA,dJ37E16.4,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience,TRIOBP
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Poids moléculaire
- 47 kDa/68 kDa/74 kDa/125 kDa/243 kDa/250 kDa/261 kDa
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ID gène
- 11078
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UniProt
- Q9H2D6
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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