VNN1 anticorps (AA 300-415)

N° du produit ABIN1683272

L’anticorps Lapin Polyclonal anti-VNN1 a été validé pour WB et IF. Il convient pour détecter VNN1 dans des échantillons de Humain.

Aperçu rapide pour VNN1 anticorps (AA 300-415) (ABIN1683272)

Antigène: VNN1 (Vanin 1 (VNN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VNN1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-VNN1 anticorps

Épitope: AA 300-415

Séquence: LLSQLDSHPS HSAVVNWTSY ASSIEALSSG NKEFKGTVFF DEFTFVKLTG VAGNYTVCQK DLCCHLSYKM SENIPNEVYA LGAFDGLHTV EGRYYLQICT LLKCKTTNLN TCGDSA

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1 (NP_004657.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur VNN1

Antigène: VNN1 (Vanin 1 (VNN1))

Autre désignation: VNN1

Sujet: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.,VNN1,HDLCQ8,Tiff66,vanin 1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Blood,Blood Pressure regulation,VNN1

Poids moléculaire: 57 kDa

ID gène: 8876

UniProt: O95497

Pathways: Negative Regulation of intrinsic apoptotic Signaling