TJP2 anticorps (AA 951-1190)
Aperçu rapide pour TJP2 anticorps (AA 951-1190) (ABIN1683322)
Antigène
Voir toutes TJP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 951-1190
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Séquence
- RSSEPVQHEE SIRKPSPEPR AQMRRAASSD QLRDNSPPPA FKPEPPKAKT QNKEESYDFS KSYEYKSNPS AVAGNETPGA STKGYPPPVA AKPTFGRSIL KPSTPIPPQE GEEVGESSEE QDNAPKSVLG KVKIFEKMDH KARLQRMQEL QEAQNARIEI AQKHPDIYAV PIKTHKPDPG TPQHTSSRPP EPQKAPSRPY QDTRGSYGSD AEEEEYRQQL SEHSKRGYYG QSARYRDTEL
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 951-1190 of human TJP2 (NP_004808.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))
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Autre désignation
- TJP2
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Sujet
- This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.,TJP2,C9DUPq21.11,DFNA51,DUP9q21.11,PFIC4,X104,ZO2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,TJP2
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Poids moléculaire
- 111-137 kDa
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ID gène
- 9414
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UniProt
- Q9UDY2
Antigène
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