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AMIGO1 anticorps (AA 554-574)

AMIGO1 Reactivité: Humain WB, IHC, ICC, IF Hôte: Souris Monoclonal S86-36 unconjugated
N° du produit ABIN1686647
  • Antigène Voir toutes AMIGO1 Anticorps
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    Épitope
    • 15
    • 12
    • 9
    • 8
    • 5
    • 5
    • 1
    AA 554-574
    Reactivité
    • 40
    • 23
    • 8
    • 4
    • 4
    • 4
    Humain
    Hôte
    • 41
    • 14
    Souris
    Clonalité
    • 41
    • 14
    Monoclonal
    Conjugué
    • 12
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AMIGO1 est non-conjugé
    Application
    • 50
    • 19
    • 16
    • 14
    • 13
    • 13
    • 11
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificité
    Detects ~60-80 kDa depending on maturity/glycosylation.
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Protein G Purified
    Immunogène
    Fusion protein amino acids 554-574 (cytoplasmic C-terminus) of human AMIGO-1
    Clone
    S86-36
    Isotype
    IgG1
  • Indications d'application
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    1 μg/ml of ABIN1686647 was sufficient for detection of AMIGO-1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    AMIGO1 (Adhesion Molecule with Ig-Like Domain 1 (AMIGO1))
    Autre désignation
    AMIGO1 (AMIGO1 Produits)
    Synonymes
    anticorps A, anticorps Amigo, anticorps ali2, anticorps AMIGO, anticorps AMIGO-1, anticorps adhesion molecule with Ig like domain 1, anticorps Amigo1, anticorps AMIGO1
    Sujet
    The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO1, AMIGO2 and AMIGO3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. They can form complexes with each other, but can also self-bind. AMIGO1, also designated Alivin2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO2 (Alivin1) is crucial for depolarization-dependent survival. Similar to AMIGO1 and AMIGO2, AMIGO3 (Alivin3) plays a role in hemophilic and/or heterophilic cell-cell interaction and signal transduction.
    ID gène
    57463
    NCBI Accession
    NP_065754
    UniProt
    Q86WK6
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