PR anticorps

N° du produit ABIN1689598

Détail du produit

Antigène: PR

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of PR expressed in E. Coli.

Clone: 2F12B4-2F12H2

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Référence

Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." dans: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, (2000) (PubMed).

Hagen, Silva, Amorim, Hagedoorn, Wassink, Haaker, Robb: "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands." dans: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 5, Issue 4, pp. 527-34, (2000) (PubMed).

Wen, Xu, Mais, Goldman, McDonnell: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." dans: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, (1994) (PubMed).

McGuire: "Prognostic factors in primary breast cancer." dans: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, (1987) (PubMed).

Bach: "Markets in kidneys." dans: Lancet, Vol. 2, Issue 8411, pp. 1102, (1984) (PubMed).

Détail du antigène

Antigène: PR

Synonymes: anticorps SPC, anticorps proline rich protein gene cluster, anticorps PR@

Sujet: PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Synonyms: PR, NR3C3, PGR

ID gène: 5241