APOL1 anticorps (AA 201-300) (AbBy Fluor® 350)

N° du produit ABIN1692596

L’anticorps Lapin Polyclonal anti-APOL1 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter APOL1 dans des échantillons de Humain.

Aperçu rapide pour APOL1 anticorps (AA 201-300) (AbBy Fluor® 350) (ABIN1692596)

Antigène: APOL1 (Apolipoprotein L, 1 (APOL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOL1 est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-APOL1 anticorps (AbBy Fluor® 350)

Épitope: AA 201-300

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APOL1/Apolipoprotein L

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur APOL1

Antigène: APOL1 (Apolipoprotein L, 1 (APOL1))

Autre désignation: APOL1/Apolipoprotein L

Sujet:

Synonyms: APO L, Apo-L, APOL, APOL I, ApoL-I, APOL1, Apolipoprotein L1, APOL1_HUMAN, APOLI, APOL1, APOL 1, APOL-1, Apolipoprotein L, Apolipoprotein L I, Apolipoprotein L-I, Apolipoprotein L1, Apolipoprotein L-1, FSGS4.

Background: Apolipoproteins are protein components of plasma lipoproteins (1). The apolipoprotein L gene family encodes six highly homologous proteins designated apoL-I to -VI, which are associated with large high density type lipoproteins (HDL) (2,3). The human apoL family maps to chromosome 22q12.1-13.1 within a 127,000-bp region (4). ApoL has been characterized as a pancreas specific, 383-amino acid protein that contains a 12-amino acid secretory signal peptide (4). The apoL genes have TATA-less promoters and contain putative sterol regulatory elements, suggesting that transcription of these genes may be coordinated with that of the low density lipoprotein receptor and genes in pathways involving the synthesis of triglycerides and cholesterol (3). ApoL homologs can undergo 10 fold changes in expression during atherosclerotic changes in vascular endothelial cells, which includes the inflammatory reaction of atherosclerotic lesions (5).

ID gène: 8542