CRYGS anticorps (AA 101-178) (AbBy Fluor® 350)

N° du produit ABIN1693897

Cet anticorps Lapin Polyclonal détecte spécifiquement CRYGS dans IF (p) et IF (cc). Il présente une réactivité envers Humain.

Aperçu rapide pour CRYGS anticorps (AA 101-178) (AbBy Fluor® 350) (ABIN1693897)

Antigène: CRYGS (Crystallin, gamma S (CRYGS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRYGS est conjugé à/à la AbBy Fluor® 350

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-CRYGS anticorps (AbBy Fluor® 350)

Épitope: AA 101-178

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Beta crystallin S

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CRYGS

Antigène: CRYGS (Crystallin, gamma S (CRYGS))

Autre désignation: Beta crystallin S

Sujet:

Synonyms: AI327013, Beta-crystallin S, CRBS_HUMAN, CRYG8, crygs, Crystallin, gamma 8, Crystallin, gamma polypeptide 8, Crystallin, gamma S, Gamma crystallin S, Gamma S crystallin, Gamma-crystallin S, Gamma-S-crystallin, recessive nuclear cataract, Opj, rncat.

Background: Crystallins are separated into two classes:taxon-specific, or enzyme, and ubiquitous. The latter classconstitutes the major proteins of vertebrate eye lens and maintainsthe transparency and refractive index of the lens. Since lenscentral fiber cells lose their nuclei during development, thesecrystallins are made and then retained throughout life, making themextremely stable proteins. Mammalian lens crystallins are dividedinto alpha, beta, and gamma families, beta and gamma crystallinsare also considered as a superfamily. Alpha and beta families arefurther divided into acidic and basic groups. Seven protein regionsexist in crystallins: four homologous motifs, a connecting peptide,and N- and C-terminal extensions. Gamma-crystallins are ahomogeneous group of highly symmetrical, monomeric proteinstypically lacking connecting peptides and terminal extensions. Theyare differentially regulated after early development. This geneencodes a protein initially considered to be a beta-crystallin butthe encoded protein is monomeric and has greater sequencesimilarity to other gamma-crystallins. This gene encodes the mostsignificant gamma-crystallin in adult eye lens tissue. Whether dueto aging or mutations in specific genes, gamma-crystallins havebeen involved in cataract formation. [provided by RefSeq, Jul2008].

ID gène: 1427