L3MBTL3 anticorps (AA 121-200) (AbBy Fluor® 350)

N° du produit ABIN1694072

L’anticorps Lapin Polyclonal anti-L3MBTL3 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter L3MBTL3 dans des échantillons de Humain.

Aperçu rapide pour L3MBTL3 anticorps (AA 121-200) (AbBy Fluor® 350) (ABIN1694072)

Antigène: L3MBTL3 (L(3)mbt-Like 3 (L3MBTL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L3MBTL3 est conjugé à/à la AbBy Fluor® 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-L3MBTL3 anticorps (AbBy Fluor® 350)

Épitope: AA 121-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human L3MBTL3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur L3MBTL3

Antigène: L3MBTL3 (L(3)mbt-Like 3 (L3MBTL3))

Autre désignation: L3MBTL3

Sujet:

Synonyms: Hl3mbt like protein, KIAA1798, l3mbt like 3 Drosophila, l3mbt like 3, L3mbt like 3 protein, Lethal3malignant brain tumor like 3 protein, MBT1, LMBL3_HUMAN.

Background: Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. PcG proteins are also required for normal maturation of myeloid progenitor cells. A putative PcG protein, L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.

ID gène: 84456