DGAT2 anticorps (AA 251-360) (AbBy Fluor® 555)

N° du produit ABIN1697017

Cet anticorps Lapin Polyclonal détecte spécifiquement DGAT2 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour DGAT2 anticorps (AA 251-360) (AbBy Fluor® 555) (ABIN1697017)

Antigène: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DGAT2 est conjugé à/à la AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-DGAT2 anticorps (AbBy Fluor® 555)

Épitope: AA 251-360

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DGAT2

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DGAT2

Antigène: DGAT2 (Diacylglycerol O-Acyltransferase 2 (DGAT2))

Autre désignation: DGAT2

Sujet:

Synonyms: DGAT2, DGAT2_HUMAN, Diacylglycerol O acyltransferase like protein 2, Diacylglycerol O-acyltransferase 2, Diacylglycerol O-acyltransferase homolog 2 mouse, Diacylglycerol O-acyltransferase homolog 2, Diacylglycerol O-acyltransferase-like protein 2 isoform 1, Diglyceride acyltransferase 2, DKFZp686A15125, GS1999full, HMFN1045.

Background: Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. Acyl-coenzyme A:diacylglycerol acyltransferase, also known as DGAT1 and ARGP1, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, such as intestinal fat absorption, lipoprotein assembly, adipose tissue form-ation and lactation. DGAT2, which has no homology to DGAT1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay. DGAT2 is expressed primarily in liver and white adipose tissue, which suggests that it plays an important role in mammalian triglyceride metabolism.

ID gène: 84649

UniProt: Q96PD7