Rad23 (AA 51-150) anticorps (AbBy Fluor® 555)

N° du produit ABIN1698017

L’anticorps anti-Rad23 Polyclonal Lapin est utilisé pour la détection de Rad23 dans des échantillons de Saccharomyces cerevisiae. Il a été validé pour WB, IF (cc) et IF (p).

Aperçu rapide pour Rad23 (AA 51-150) anticorps (AbBy Fluor® 555) (ABIN1698017)

Antigène: Rad23

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 51-150

Réactivité croisée: Saccharomyces cerevisiae

Réactivité croisée (Details): Saccharomyces cerevisiae

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae Rad23

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Rad23

Sujet:

Synonyms: DNA repair protein RAD23, UV excision repair protein RAD23, RAD23_YEAST, YEL037C, SYGP-ORF29.

Background: The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1). RAD23 resembles the other DNA repair genes, RAD2, RAD6, RAD7, RAD18, and RAD54, all of which also exhibit increased transcription in response to DNA damage and during meiosis (2). RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3). RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3). Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4). Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4). In addition to a role in DNA repair events in yeast, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5).

ID gène: 856674