PTCHD2 anticorps (AA 401-500) (AbBy Fluor® 647)

N° du produit ABIN1698908

L’anticorps Lapin Polyclonal anti-PTCHD2 a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter PTCHD2 dans des échantillons de Humain.

Aperçu rapide pour PTCHD2 anticorps (AA 401-500) (AbBy Fluor® 647) (ABIN1698908)

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTCHD2 est conjugé à/à la AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PTCHD2 anticorps (AbBy Fluor® 647)

Épitope: AA 401-500

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PTCHD2/DISP3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PTCHD2

Antigène: PTCHD2 (Patched Domain Containing 2 (PTCHD2))

Autre désignation: PTCHD2/DISP3

Sujet:

Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.

Background: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

ID gène: 57540