GM2A anticorps (AA 131-193) (Biotin)

N° du produit ABIN1700012

L’anticorps Lapin Polyclonal anti-GM2A a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter GM2A dans des échantillons de Humain et Rat.

Aperçu rapide pour GM2A anticorps (AA 131-193) (Biotin) (ABIN1700012)

Antigène: GM2A (GM2 Ganglioside Activator (GM2A))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GM2A est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GM2A anticorps (Biotin)

Épitope: AA 131-193

Réactivité croisée: Humain, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GM2A/SAP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GM2A

Antigène: GM2A (GM2 Ganglioside Activator (GM2A))

Autre désignation: GM2A

Sujet:

Synonyms: SAP-3, GM2-AP, Ganglioside GM2 activator, Cerebroside sulfate activator protein, Sphingolipid activator protein 3, GM2A

Background: The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.

ID gène: 2760

UniProt: P17900