Lethal (2) I16 (L(2)I16) (AA 701-785) anticorps (Biotin)

N° du produit ABIN1700040

Cet anticorps anti-Lethal (2) I16 Polyclonal Lapin conjugué à Biotin (ABIN1700040) détecte spécifiquement Lethal (2) I16 dans WB, ELISA, IHC (fro) et IHC (p). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Lethal (2) I16 (L(2)I16) (AA 701-785) anticorps (Biotin) (ABIN1700040)

Antigène: Lethal (2) I16 (L(2)I16)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: AA 701-785

Réactivité croisée: Souris

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IFI16

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Lethal (2) I16 (L(2)I16)

Autre désignation: I16

Sujet:

Synonyms: I16, Gamma interferon inducible protein 16, Gamma-interferon-inducible protein i16, IF16_HUMAN, i204, NGIP1, interferon activated gene 204, Interferon gamma induced protein I 16, Interferon gamma inducible protein 16, Interferon-inducible myeloid dferentiation transcriptional activator, p204, PYHIN2.

Background: IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

ID gène: 3428

UniProt: Q16666