Ly6c/CD59 anticorps (AA 26-102) (Biotin)
Aperçu rapide pour Ly6c/CD59 anticorps (AA 26-102) (Biotin) (ABIN1700055)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 26-102
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Ly6c
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Ly6c/CD59 (LY6C) (Lymphocyte Antigen 6 Complex, Locus C (LY6C))
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Autre désignation
- Ly6c/CD59
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Sujet
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Synonyms: Ly 6c, Ly6c protein, Ly-6C, Ly6c1, Ly6c2, Lymphocyte antigen 6 complex, Lymphocyte antigen 6 complex locus C, Lymphocyte antigen 6C, Lymphocyte antigen 6C1, Lymphocyte antigen 6C2, Lymphocyte antigen Ly 6C, CD59_HUMAN.
Background: The gene encoding the mouse alloantigen, Ly-6C, maps to chromosome 15 and encodes a 131 amino acid protein that belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 Molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6C is predominantly expressed on murine peripheral CD8 T cells. Ly-6C is involved in endothelial adhesion, the killing of target cells by CTLs, inducing TCR-mediated activation of IL-2 and IFN-?production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation.
Antigène
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