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Ly6c/CD59 anticorps (AA 26-102) (Biotin)

Cet anticorps anti-Ly6c/CD59 est un anticorps Lapin Polyclonal détectant Ly6c/CD59 dans WB, ELISA, IHC (fro) et IHC (p). Adapté pour Humain.
N° du produit ABIN1700055

Aperçu rapide pour Ly6c/CD59 anticorps (AA 26-102) (Biotin) (ABIN1700055)

Antigène

Ly6c/CD59 (LY6C) (Lymphocyte Antigen 6 Complex, Locus C (LY6C))

Reactivité

Humain

Hôte

  • 14
Lapin

Clonalité

  • 14
Polyclonal

Conjugué

  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Ly6c/CD59 est conjugé à/à la Biotin

Application

  • 14
  • 13
  • 13
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    AA 26-102

     Réactivité croisée

    Humain

    Purification

    Purified by Protein A.

    Immunogène

    KLH conjugated synthetic peptide derived from human Ly6c

    Isotype

    IgG
  • Indications d'application

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Agent conservateur

    ProClin

    Précaution d'utilisation

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C for 12 months.

    Date de péremption

    12 months
  • Antigène

    Ly6c/CD59 (LY6C) (Lymphocyte Antigen 6 Complex, Locus C (LY6C))

    Autre désignation

    Ly6c/CD59

    Sujet

    Synonyms: Ly 6c, Ly6c protein, Ly-6C, Ly6c1, Ly6c2, Lymphocyte antigen 6 complex, Lymphocyte antigen 6 complex locus C, Lymphocyte antigen 6C, Lymphocyte antigen 6C1, Lymphocyte antigen 6C2, Lymphocyte antigen Ly 6C, CD59_HUMAN.

    Background: The gene encoding the mouse alloantigen, Ly-6C, maps to chromosome 15 and encodes a 131 amino acid protein that belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 Molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6C is predominantly expressed on murine peripheral CD8 T cells. Ly-6C is involved in endothelial adhesion, the killing of target cells by CTLs, inducing TCR-mediated activation of IL-2 and IFN-?production in CD8 T cells and the homing of CD8 T cells. In addition, Ly-6C may act as a signaling molecule of LFA-1 activation.

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