Cadherin 12 anticorps (AA 291-390) (Biotin)

N° du produit ABIN1700242

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin 12 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Rat.

Aperçu rapide pour Cadherin 12 anticorps (AA 291-390) (Biotin) (ABIN1700242)

Antigène: Cadherin 12

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 12 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Cadherin 12 anticorps (Biotin)

Épitope: AA 291-390

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CDH12

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Cadherin 12

Antigène: Cadherin 12

Autre désignation: CDH12

Sujet:

Synonyms: Br cadherin, BR-cadherin, Brain cadherin, CAD12_HUMAN, cadherin 12 N cadherin 2, Cadherin 12, Cadherin 12 precursor, Cadherin 12 type 2 N cadherin 2, Cadherin 12 type 2, Cadherin neural type 2, Cadherin-12, CDH12, CDHB, FLJ34857, N cadherin 2, N-cadherin 2, Neural type cadherin 2, Neuronal cadherin 2.

Background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4). Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6). The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function (7). BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8).