ITPA anticorps (AA 1-100) (Biotin)

N° du produit ABIN1700347

Cet anticorps Lapin Polyclonal détecte spécifiquement ITPA dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour ITPA anticorps (AA 1-100) (Biotin) (ABIN1700347)

Antigène: ITPA (Inosine Triphosphatase (ITPA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITPA est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ITPA anticorps (Biotin)

Épitope: AA 1-100

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Inosine triphosphate pyrophosphatase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ITPA

Antigène: ITPA (Inosine Triphosphatase (ITPA))

Autre désignation: Inosine triphosphate pyrophosphatase

Sujet:

Synonyms: ITPase, C20orf37, dJ794I6.3, HLC14-06-P, Inosine triphosphatase nucleoside triphosphate pyrophosphatase, Inosine triphosphatase, inosine triphosphatase-A, Inosine triphosphate pyrophosphatase, Inosine triphosphate pyrophosphohydrolase, Itpa, ITPA_HUMAN, ITPase, My049, My049 protein, Non canonical purine NTP pyrophosphatase, Non standard purine NTP pyrophosphatase, NTPase, nucleoside triphosphate diphosphatase, Nucleoside triphosphate pyrophosphatase, OK/SW-cl.9, OTTHUMP00000030094, OTTHUMP00000160459, Putative oncogene protein hlc14-06-p.

Background: ITPase (inosine triphosphate pyrophosphatase) is also known as putative oncogene protein hlc14-06-p or ITPA (inosine triphosphatase (nucleoside triphosphate pyrophosphatase)) and is a 194 amino acid protein. ITPase is abundantly expressed in heart, liver, sex glands, thyroid and adrenal gland, and is localized to the cytoplasm in the cell. ITPase catalyzes the pyrophosphohydrolysis of both ITP (inosine triphosphate) and dITP (deoxyinosine triphosphate) to IMP (inosine monophosphate) and diphosphate. IMP can be used as a substrate for purine nucleotide pathways. IMP can be phosphorylated to ITP, and ITPase can regulate the concentration of ITP in the cell by converting ITP back to IMP. Defects in ITPase result in ITPase deficiency which is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.

ID gène: 3704