SKAP2 anticorps (AA 1-100) (Biotin)

N° du produit ABIN1700391

Détail du produit anti-SKAP2 anticorps (Biotin)

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKAP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SCAP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SKAP2

Antigène: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Autre désignation: SCAP2 (SKAP2 Produits)

Synonymes: anticorps scap2, anticorps 2610021A10Rik, anticorps AA960083, anticorps BB137539, anticorps RA70, anticorps SKAP-HOM, anticorps Saps, anticorps Scap2, anticorps mSKAP55R, anticorps PRAP, anticorps SAPS, anticorps SCAP2, anticorps SKAP55R, anticorps Scap55r, anticorps SKAP55, anticorps si:dz227h09.6, anticorps si:dz31b14.4, anticorps zgc:158223, anticorps zgc:65975, anticorps src kinase associated phosphoprotein 2 L homeolog, anticorps SRC kinase associated phosphoprotein 2, anticorps src family associated phosphoprotein 2, anticorps src kinase associated phosphoprotein 2, anticorps skap2.L, anticorps CCC13826_0176, anticorps Skap2, anticorps SKAP2, anticorps skap2

Sujet:

Synonyms: Fyn associated phosphoprotein SKAP55 homologue, MGC10411, MGC33, PRAP, Pyk2/RAFTK associated protein, Pyk2/RAFTK-associated protein, RA70, Retinoic acid-induced protein 70, SAPS, SKAP-55HOM, SKAP-HOM, skap2, SKAP2_HUMAN, SKAP55 homolog, SKAP55R, Src associated adaptor protein, Src family associated phosphoprotein 2, Src family-associated phosphoprotein 2, src kinase associated phosphoprotein of 55 related protein, Src kinase-associated phosphoprotein 2, Src kinase-associated phosphoprotein 55-related protein, Src-associated adapter protein with PH and SH3 domains.

Background: Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.