DYX1C1 anticorps (AA 51-120) (Biotin)
Aperçu rapide pour DYX1C1 anticorps (AA 51-120) (Biotin) (ABIN1700546)
Antigène
Voir toutes DYX1C1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 51-120
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Réactivité croisée
- Souris, Rat
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Homologie
- Human,Dog,Cow,Chicken,Zebrafish
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human DYX1C1
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))
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Autre désignation
- DYX1C1
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Sujet
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Synonyms: Dyslexia susceptibility 1 candidate 1, Dyslexia susceptibility 1 candidate gene 1 protein, DYX1, DYX1C1, DYXC1, DYXC1_HUMAN, EKN1, FLJ37882, MGC70618, RD.
Background: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2,15)(q11,q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
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ID gène
- 161582
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Antigène
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