HDAC5 anticorps (pSer498) (Biotin)

N° du produit ABIN1700578

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC5 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Poulet.

Aperçu rapide pour HDAC5 anticorps (pSer498) (Biotin) (ABIN1700578)

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC5 est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HDAC5 anticorps (Biotin)

Épitope: pSer498

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HDAC5 around the phosphorylation site of Ser498

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HDAC5

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Autre désignation: HDAC5

Sujet:

Synonyms: HDAC5Ser498, HDAC5S498, p-HDAC5Ser498, p-HDAC5S498, HD 5, HD5, HDAC 5, Histone deacetylase 5, KIAA0600, NY CO 9, Antigen NY CO 9, FLJ90614, HDAC5_HUMAN, Antigen NY-CO-9.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process