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PBX2 anticorps (AA 265-370) (Biotin)

PBX2 Reactivité: Humain WB, ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN1700716
  • Antigène Voir toutes PBX2 Anticorps
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Épitope
    • 14
    • 8
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 265-370
    Reactivité
    • 43
    • 16
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 38
    • 6
    Lapin
    Clonalité
    • 39
    • 5
    Polyclonal
    Conjugué
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PBX2 est conjugé à/à la Biotin
    Application
    • 41
    • 20
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human PBX2
    Isotype
    IgG
    Top Product
    Discover our top product PBX2 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))
    Autre désignation
    PBX2 (PBX2 Produits)
    Synonymes
    anticorps G17, anticorps HOX12, anticorps PBX2MHC, anticorps AU043397, anticorps pbxy, anticorps wu:fb73g03, anticorps hox12, anticorps pbx2mhc, anticorps PBX2P1, anticorps PBX homeobox 2, anticorps pre B cell leukemia homeobox 2, anticorps pre-B-cell leukemia homeobox 2, anticorps pre-B-cell leukemia homeobox 2 L homeolog, anticorps PBX2, anticorps Pbx2, anticorps pbx2, anticorps pbx2.L
    Sujet

    Synonyms: G17, Homeobox protein PBX2, HOX12, PBX2MHC, pre-B-cell leukemia homeobox 2, pre-B-cell leukemia transcription factor 2, Protein G17, PBX2_HUMAN.

    Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

    ID gène
    5089
    Pathways
    Skeletal Muscle Fiber Development
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