DMWD anticorps (AA 501-600) (Biotin)

N° du produit ABIN1700853

Cet anticorps anti-DMWD est un anticorps Lapin Polyclonal détectant DMWD dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour DMWD anticorps (AA 501-600) (Biotin) (ABIN1700853)

Antigène: DMWD (Dystrophia Myotonica, WD Repeat Containing (DMWD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMWD est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DMWD anticorps (Biotin)

Épitope: AA 501-600

Homologie: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DMWD/DMRN9

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DMWD

Antigène: DMWD (Dystrophia Myotonica, WD Repeat Containing (DMWD))

Autre désignation: DMWD/DMRN9

Sujet:

Synonyms: dystrophia myotonica containing WD repeat mot,D19S593E, DM 9, DM9, DMR N9, DMR N9 protein, DMRN 9, DMRN9, DMWD, DMWD_HUMAN, Dystrophia myotonica containing WD repeat mot, Dystrophia myotonica containing WD repeat mot protein, Dystrophia myotonica WD repeat containing protein, Dystrophia myotonica WD repeat-containing protein, Dystrophia myotonica-containing WD repeat mot protein, Gene59, Protein 59, Protein DMR-N9.

Background: DMWD is a 674 amino acid protein containing five WD repeats. DMWD may play a role in the development of mental symptoms in severe cases of myotonic dystrophy, a chronic multisystemic disease characterized by wasting of the muscles, heart conduction defects, cataracts, endocrine changes and myotonia. The DMWD gene is located upstream of the DMPK gene and is prominently expressed in tissues affected in myotonic dystrophy patients. DMWD may also contribute to regulation in meiosis. DMWD is expressed in kidney and spleen, with strongest expression in brain, liver and testis. The gene encoding DMWD maps to human chromosome 19q13.32 and mouse chromosome 7 A3.

ID gène: 1762