FBLN2 anticorps (AA 501-600) (Biotin)

N° du produit ABIN1700863

Cet anticorps Lapin Polyclonal détecte spécifiquement FBLN2 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour FBLN2 anticorps (AA 501-600) (Biotin) (ABIN1700863)

Antigène: FBLN2 (Fibulin 2 (FBLN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBLN2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FBLN2 anticorps (Biotin)

Épitope: AA 501-600

Homologie: Human,Mouse,Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Fibulin 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FBLN2

Antigène: FBLN2 (Fibulin 2 (FBLN2))

Autre désignation: Fibulin 2

Sujet:

Synonyms: Fibulin-2, Fbln2, FBLN2_HUMAN, FIBL-2, Fibulin-2, OTTHUMP00000216670, OTTHUMP00000216671, OTTHUMP00000216672.

Background: Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.

ID gène: 2199