CAPG anticorps (AA 251-348) (Biotin)

N° du produit ABIN1700984

L’anticorps Lapin Polyclonal anti-CAPG a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter CAPG dans des échantillons de Humain.

Aperçu rapide pour CAPG anticorps (AA 251-348) (Biotin) (ABIN1700984)

Antigène: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAPG est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CAPG anticorps (Biotin)

Épitope: AA 251-348

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Actin Regulatory Protein CAPG

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CAPG

Antigène: CAPG (Capping Protein (Actin Filament), Gelsolin-Like (CAPG))

Autre désignation: Actin Regulatory Protein CAPG

Sujet:

Synonyms: Actin capping protein GCAP39, Actin regulatory protein CAP G, Actin regulatory protein CAP-G, AFCP, CAPG, CAPG_HUMAN, Capping protein actin filament gelsolin like, Capping protein gelsolin like, gCap39, Gelsolin like capping protein, Macrophage capping protein, Macrophage-capping protein, mbh1, MCP, Myc basic mot homolog 1.

Background: Caldesmon, Filamin 1, Nebulin, Plastin, ADF, Gelsolin, CapG, Dematin and Cofilin are differentially expressed Actin-binding proteins. Both muscular (CDh) and non-muscular (CD1) forms of Caldesmon bind to Actin as well as to Calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CD1 is widely expressed in non-muscle tissues and cells. CapG, also designated Actin-regulatory protein and macrophage-capping protein, is a macrophage-specific protein that reversibly blocks the barbed ends of Actin filaments, but does not sever preformed ones. The interactions of CapG with Actin may be important in the regulation of nuclear and cytoplasmic structures. CapG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm.

ID gène: 822

Pathways: Regulation of Actin Filament Polymerization