DZIP3 anticorps (AA 451-550) (Biotin)

N° du produit ABIN1701023

L’anticorps Lapin Polyclonal anti-DZIP3 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter DZIP3 dans des échantillons de Souris.

Aperçu rapide pour DZIP3 anticorps (AA 451-550) (Biotin) (ABIN1701023)

Antigène: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DZIP3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-DZIP3 anticorps (Biotin)

Épitope: AA 451-550

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DZIP3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur DZIP3

Antigène: DZIP3 (DAZ Interacting Protein 3, Zinc Finger (DZIP3))

Autre désignation: DZIP3

Sujet:

Synonyms: DAZ-interacting protein 3, E3 ubiquitin-protein ligase DZIP3, hRUL138, KIAA0675, RNA-binding ubiquitin ligase of 138 kDa, DZIP3_HUMAN.

Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). DZIP3 (DAZ interacting protein 3, zinc finger), also known as UURF2 or hRUL138, is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.

ID gène: 9666