FOSB anticorps (pSer27) (Biotin)

N° du produit ABIN1701082

Cet anticorps Lapin Polyclonal détecte spécifiquement FOSB dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour FOSB anticorps (pSer27) (Biotin) (ABIN1701082)

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOSB est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-FOSB anticorps (Biotin)

Épitope: pSer27

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Fos B around the phosphorylation site of Ser27

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FOSB

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Autre désignation: FosB

Sujet:

Synonyms: Fos B phospho S27, p-Fos B phospho S27, p-FosB phospho S27, FBJ murine osteosarcoma viral oncogene homolog B, FOS B, FOS-B, FBJ osteosarcoma oncogene B, FosB, G0/G1 switch regulatory protein 3, G0S3, GOS3, GOSB, MGC42291, Oncogene FOS B, Protein fosB, fosB, G0/G1 switch regulatory protein 3, G0S3, GOS 3, GOS B, GOSB, Oncogene FOS B, Oncogene FOSB, Protein fos B, DKFZp686C0818, FOSB_HUMAN.

Background: The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70 % homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

ID gène: 2354