FBLN4 anticorps (AA 331-443) (Biotin)

N° du produit ABIN1701235

Cet anticorps Lapin Polyclonal détecte spécifiquement FBLN4 dans WB, ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour FBLN4 anticorps (AA 331-443) (Biotin) (ABIN1701235)

Antigène: FBLN4 (Fibulin 4 (FBLN4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBLN4 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FBLN4 anticorps (Biotin)

Épitope: AA 331-443

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EFEMP2/Fibulin 4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Références pour anticorps anti-FBLN4 (Biotin) (ABIN1701235)

Dekker, van Geemen, van den Bogaerdt, Driessen-Mol, Aikawa, Smits: "Sheep-Specific Immunohistochemical Panel for the Evaluation of Regenerative and Inflammatory Processes in Tissue-Engineered Heart Valves." dans: Frontiers in cardiovascular medicine, Vol. 5, pp. 105, (2018) (PubMed).

Détails sur FBLN4

Antigène: FBLN4 (Fibulin 4 (FBLN4))

Autre désignation: EFEMP2/Fibulin 4

Sujet:

Synonyms: EFEMP2, EGF containing fibulin like extracellular matrix protein 2, EGF-containing fibulin-like extracellular matrix protein 2, FBLN 4, FBLN4, FBLN4_HUMAN, FIBL 4, FIBL-4, FIBL4, Fibulin4, Fibulin-4, MBP 1, MBP1, Mutant p53 binding protein 1, Protein UPH1, UPH 1, UPH1, UPH1 protein.

Background: Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-4, also known as EFEMP2 (EGF-containing fibulin-like extracellular matrix protein 2), MBP1 or UPH1 is a 443 amino acid secreted protein that contains six EGF-like calcium-binding domains and belongs to the fibulin family. Expressed ubiquitously with highest expression in heart, Fibulin-4 is essential for connective tissue development and elastic fiber formation, and may also play an important role in vascular patterning and collagen biosynthesis. Defects in the gene encoding Fibulin-4 are associated with autosomal recessive cutis laxa type I (CL type I), a connective tissue disorder that is inherited in both an autosomal dominant and an autosomal recessive manner and is characterized by inelastic tissue in all affected areas of the body.

ID gène: 30008