GK2 anticorps (AA 101-200) (Biotin)

N° du produit ABIN1701303

Cet anticorps anti-GK2 est un anticorps Lapin Polyclonal détectant GK2 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain et Rat.

Aperçu rapide pour GK2 anticorps (AA 101-200) (Biotin) (ABIN1701303)

Antigène: GK2 (Glycerol Kinase 2 (GK2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GK2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GK2 anticorps (Biotin)

Épitope: AA 101-200

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GK2/Glycerol kinase 2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GK2

Antigène: GK2 (Glycerol Kinase 2 (GK2))

Autre désignation: GK2/Glycerol kinase 2

Sujet:

Synonyms: ATP:glycerol 3 phosphotransferase, EC 2.7.1.30, GK 2, GK, GKP2, GKTA, Glycerokinase, Glycerol kinase 2, Glycerol kinase testis specic 2, GLPK2_HUMAN.

Background: GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

ID gène: 2712