GBA3 anticorps (AA 151-250) (Biotin)

N° du produit ABIN1701593

L’anticorps Lapin Polyclonal anti-GBA3 a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter GBA3 dans des échantillons de Humain.

Aperçu rapide pour GBA3 anticorps (AA 151-250) (Biotin) (ABIN1701593)

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA3 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-GBA3 anticorps (Biotin)

Épitope: AA 151-250

Homologie: Human,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GBA3/CBG

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur GBA3

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3/CBG

Sujet:

Synonyms: CBG, CBGL1, Cytosolic beta glucosidase, Cytosolic beta glucosidase like protein 1, Cytosolic beta-glucosidase, Cytosolic beta-glucosidase-like protein 1, GBA3, GBA3_HUMAN, GLUC, Glucosidase beta acid 3, Klotho related protein.

Background: CBG is a monomeric enzyme involved in the absorption and metabolism of flavonoid glucosides. CBG is found predominately in the liver, but is also located in tissues such as spleen, small intestine and kidney. Through its catalytic activity, CBG is able to hydrolyze a variety of glycosides including phytoestrogens, cyanogens, and flavonols. Although its catalytic activity extends to many dietary flavonoids, CBG has increased specificity for hydrophobic aglycones such as beta-D-glucoside and beta-D-galactoside. Hydrolysis is inhibited by sodium taurocholate and glucosyl-sphingosine, both of which regulate CBG enzymatic activity. Deficiencies in CBG have been implicated in Gaucher?s disease, a lysosomal storage disease that causes a build up of fatty material in the spleen, liver, lung and kidneys.

ID gène: 57733