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GCNT7 anticorps (AA 241-430) (Cy3)

GCNT7 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Cy3
N° du produit ABIN1702122
  • Antigène Voir toutes GCNT7 Anticorps
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    Épitope
    • 14
    • 10
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 241-430
    Reactivité
    • 41
    • 4
    • 3
    Humain
    Hôte
    • 41
    Lapin
    Clonalité
    • 41
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GCNT7 est conjugé à/à la Cy3
    Application
    • 35
    • 18
    • 12
    • 12
    • 8
    • 7
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GCNT7
    Isotype
    IgG
    Top Product
    Discover our top product GCNT7 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GCNT7 (Glucosaminyl (N-Acetyl) Transferase Family Member 7 (GCNT7))
    Autre désignation
    GCNT7 (GCNT7 Produits)
    Synonymes
    anticorps A330041C17Rik, anticorps gnt, anticorps C20orf105, anticorps dJ1153D9.2, anticorps gcnt, anticorps C17H20orf105, anticorps glucosaminyl (N-acetyl) transferase family member 7, anticorps Gcnt7, anticorps GCNT7
    Sujet

    Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 7, Beta-1, Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, C20orf105, GCNT, GCNT7, GCNT7_HUMAN, glucosaminyl N-acetyl transferase family member 7.

    Background: Belonging to the glycosyltransferase 14 family, GCNT7, also known as Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7, is a 430 amino acid glycosyltransferase that is localized to the Golgi apparatus. Other members of this family include GCNT1, GCNT2, GCNT3, GCNT4 and GCNT6. GCNT1 has been shown to play an important regulatory role in the biosynthesis of mucin-type O-glycans, which serve as ligands in cell adhesion. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectin proteins. Since downregulation of Selectin ligand expression has been shown to inhibit tissue infiltration, glycosyltransferase 14 family members represent potential drug targets for the treatment of inflammatory disorders and other pathologies involving Selectin proteins.

    ID gène
    140687
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