SH2B3 anticorps (AA 161-260) (Cy3)

N° du produit ABIN1702168

Cet anticorps Lapin Polyclonal détecte spécifiquement SH2B3 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour SH2B3 anticorps (AA 161-260) (Cy3) (ABIN1702168)

Antigène: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH2B3 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SH2B3 anticorps (Cy3)

Épitope: AA 161-260

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Monkey

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human LNK

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SH2B3

Antigène: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Autre désignation: LNK

Sujet:

Synonyms: IDDM20,Lymphocyte adapter protein,Lymphocyte specic adapter protein,Lymphocyte specic adapter protein Lnk,Lymphocyte-specic adapter protein Lnk,SH2B adapter protein 3,SH2B adaptor protein 3,Sh2b3,SH2B3_HUMAN,Signal transduction protein Lnk.

Background: APS (adapter molecule containing PH and SH2 domains), SH2-B and Lnk compose a family of adapter proteins, which contain a pleckstrin homology (PH) domain, an SH2 domain and a tyrosine phosphorylation site. Stimulation of B cell receptor (BCR) or T cell receptor (TCR) results in the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of BCR, TCR and several substrates. APS, SH2-B and Lnk may bind to the ITAM domain of BCR and TCR. Lnk is tyrosine phosphorylated in response to TCR stimulation and APS has been shown to be tyrosine phosphorylated in response to BCR stimulation.