GAPVD1 anticorps (AA 1151-1250) (Cy3)

N° du produit ABIN1702309

Cet anticorps Lapin Polyclonal détecte spécifiquement GAPVD1 dans WB, IF (cc) et IF (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour GAPVD1 anticorps (AA 1151-1250) (Cy3) (ABIN1702309)

Antigène: GAPVD1 (GTPase Activating Protein and VPS9 Domains 1 (GAPVD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GAPVD1 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GAPVD1 anticorps (Cy3)

Épitope: AA 1151-1250

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GAPVD1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GAPVD1

Antigène: GAPVD1 (GTPase Activating Protein and VPS9 Domains 1 (GAPVD1))

Autre désignation: GAPVD1

Sujet:

Synonyms: GAPEX 5, GAPVD1, GTPase activating protein and VPS9 domains 1, KIAA1521, Rab5 activating protein 6, RAP6, GAPD1_HUMAN.

Background: GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.

ID gène: 26130