GEMIN7 anticorps (AA 21-120) (Cy3)

N° du produit ABIN1702365

Cet anticorps anti-GEMIN7 Polyclonal Lapin conjugué à Cy3 (ABIN1702365) détecte spécifiquement GEMIN7 dans FACS, IF (cc) et IF (p). L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour GEMIN7 anticorps (AA 21-120) (Cy3) (ABIN1702365)

Antigène: GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GEMIN7 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GEMIN7 anticorps (Cy3)

Épitope: AA 21-120

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Gemin 7

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GEMIN7

Antigène: GEMIN7 (Gem (Nuclear Organelle) Associated Protein 7 (GEMIN7))

Autre désignation: Gemin 7

Sujet:

Synonyms: SIP3, Gemin7, Gemin-7, GEMI7_HUMAN.

Background: Gemin7 is a 131 amino acid protein encoded by the mouse gene Gemin7. Gemin7, along with Gemin6, is a significant component of the the large multiprotein human SMN complex. The SMN complex functions as an assembly machine for small nuclear ribonucleoproteins (snRNPs)-the major components of the spliceosome. The survival of motor neurons (SMN) protein, a product of the disease gene of the common neurodegenerative disease, spinal muscular atrophy, is also part of the SMN complex. Although Gemin6 and Gemin7 have no significant sequence similarity with Sm proteins, both adopt canonical Sm folds. Moreover, Gemin6 and Gemin7 exist as a heterodimer, and interact with each other via an interface similar to that which mediates interactions among the Sm proteins. The Gemin6/Gemin7 complex binds to Sm proteins and might help organize Sm proteins for formation of Sm rings on snRNA targets.

ID gène: 79760

Pathways: Ribonucleoprotein Complex Subunit Organization