HDAC5 anticorps (pSer498) (Cy3)

N° du produit ABIN1702391

L’anticorps anti-HDAC5 Polyclonal Lapin est utilisé pour la détection de HDAC5 dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour HDAC5 anticorps (pSer498) (Cy3) (ABIN1702391)

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC5 est conjugé à/à la Cy3

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-HDAC5 anticorps (Cy3)

Épitope: pSer498

Fonction: phospho-HDAC5 (Ser498) Polyclonal Antibody, Cy3 Conjugated

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HDAC5 around the phosphorylation site of Ser498

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IF(1:50-200), Flow-Cyt(1 μg/Test)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HDAC5

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Autre désignation: HDAC5

Sujet:

Synonyms: HDAC5Ser498, HDAC5S498, p-HDAC5Ser498, p-HDAC5S498, HD 5, HD5, HDAC 5, Histone deacetylase 5, KIAA0600, NY CO 9, Antigen NY CO 9, FLJ90614, HDAC5_HUMAN, Antigen NY-CO-9.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process