Galnt1 anticorps (AA 101-200) (Cy5)

N° du produit ABIN1704301

Cet anticorps Lapin Polyclonal détecte spécifiquement Galnt1 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Galnt1 anticorps (AA 101-200) (Cy5) (ABIN1704301)

Antigène: Galnt1 (Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Galnt1 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Galnt1 anticorps (Cy5)

Épitope: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GALNT1/GalNAc-T1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Galnt1

Antigène: Galnt1 (Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1))

Autre désignation: GALNT1/GalNAc-T1

Sujet:

Synonyms: GALNAC T1, GalNAc transferase 1, GalNAc-T1, GALNT 1, GALNT1, GALT1_HUMAN, Polypeptide GalNAc transferase 1, Polypeptide N acetylgalactosaminyltransferase 1, Polypeptide N-acetylgalactosaminyltransferase 1 soluble form, pp GaNTase 1, pp-GaNTase 1, Protein UDP acetylgalactosaminyltransferase 1, Protein-UDP acetylgalactosaminyltransferase 1, UDP GalNAc:polypeptide N acetylgalactosaminyltransferase 1, UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1 GalNAc T1, UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 1, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1.

Background: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T1, also known as GALNT1 (Polypeptide N-acetylgalactosaminyltransferase 1), is a ubiquitously expressed 559 amino acid single-pass type II membrane protein that localizes to the Golgi apparatus and, like other GalNAc-Ts, contains a stem region and a C-terminal ricin/lectin-like domain. GalNAc-T1 catalyzes the first reaction in O-linked oligosaccharide biosynthesis, namely the transfer of an N-acetyl-D-galactosamine residue to a protein acceptor. GalNAc-T1 uses calcium and manganese as cofactors. Due to alternative splicing events, two GalNAc-T1 isoforms are expressed.

ID gène: 2589