KNDC1 anticorps (AA 1601-1749) (Cy5)

N° du produit ABIN1704406

Cet anticorps Lapin Polyclonal détecte spécifiquement KNDC1 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour KNDC1 anticorps (AA 1601-1749) (Cy5) (ABIN1704406)

Antigène: KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KNDC1 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-KNDC1 anticorps (Cy5)

Épitope: AA 1601-1749

Homologie: Human,Mouse,Rat,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KNDC1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KNDC1

Antigène: KNDC1 (Kinase Non-Catalytic C-Lobe Domain (KIND) Containing 1 (KNDC1))

Autre désignation: KNDC1

Sujet:

Synonyms: Cerebral protein 9, FLJ25027, hucep-9, KIAA1768, Kinase non-catalytic C-lobe domain-containing protein 1, KIND domain-containing protein 1, KNDC1, Protein very KIND, Ras-GEF domain-containing family member 2, RASGEF2, VKIND, VKIND_HUMAN, bB439H18.3, C10orf23.

Background: KNDC1 is a 1,749 amino acid protein that contains two KIND domains and an N-terminal Ras-GEF domain. Expressed in the cerebral cortex, KNDC1 is a likely guanine nucleotide exchange factor (GEF). Existing as six alternatively spliced isoforms, the gene encoding KNDC1 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5 % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman?s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

ID gène: 85442