BAMBI anticorps (AA 101-200) (Cy5)

N° du produit ABIN1704611

L’anticorps Lapin Polyclonal anti-BAMBI a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter BAMBI dans des échantillons de Humain, Rat, Souris et Porc.

Aperçu rapide pour BAMBI anticorps (AA 101-200) (Cy5) (ABIN1704611)

Antigène: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Reactivité: Humain, Rat, Souris, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAMBI est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BAMBI anticorps (Cy5)

Épitope: AA 101-200

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Dog,Cow,Sheep,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BAMBI

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BAMBI

Antigène: BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))

Autre désignation: BAMBI

Sujet:

Synonyms: NMA, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA, BAMBI

Background: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

ID gène: 25805

UniProt: Q13145