QRFPR anticorps (AA 151-250) (Cy7)

N° du produit ABIN1707685

Cet anticorps Lapin Polyclonal détecte spécifiquement QRFPR dans WB, IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour QRFPR anticorps (AA 151-250) (Cy7) (ABIN1707685)

Antigène: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp QRFPR est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-QRFPR anticorps (Cy7)

Épitope: AA 151-250

Réactivité croisée: Humain

Homologie: Mouse,Rat,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human G protein coupled receptor 103

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur QRFPR

Antigène: QRFPR (Pyroglutamylated RFamide Peptide Receptor (QRFPR))

Autre désignation: GPR103

Sujet:

Synonyms: AQ27, G protein coupled receptor 103, G-protein coupled receptor 103, G protein-coupled receptor 103, Orexigenic neuropeptide QRFP receptor, Pyroglutamylated RFamide peptide receptor, QRFP receptor, QRFPR, SP9155, QRFPR_HUMAN, GPCR GPR103.

Background: G protein-coupled receptors (GPRs) are a protein family of transmembrane receptors that transmit an extracellular signal (ligand binding) into an intracellular signal (G protein activation). GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. All of the receptors have seven membrane-spanning domains and the extracellular parts of the receptor can be glycosylated. These extracellular loops also contain two highly conserved cysteine residues which create disulfide bonds to stabilize the receptor structure. GPR103 is a 455-amino acid protein with highest expression in the brain, retina, trigeminal ganglion, hypothalamus and vestibular nucleus. In peripheral tissues, GPR103 is expressed only in the heart, kidney and testis. GPR103 may regulate adrenal function. A hypothalamic neuropeptide of the RFamide family (26RFa) acts as an endogenous ligand for GPR103.

ID gène: 84109