Glutamate Receptor 1 anticorps (pThr856) (Cy7)
Aperçu rapide pour Glutamate Receptor 1 anticorps (pThr856) (Cy7) (ABIN1708147)
Antigène
Voir toutes Glutamate Receptor 1 (GLUR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr856
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Réactivité croisée
- Rat
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Homologie
- Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Glutamate Receptor 1 around the phosphorylation site of Thr856
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- Glutamate Receptor 1 (GLUR1)
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Autre désignation
- GluR1
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Sujet
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Synonyms: Glutamate receptor 1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1, GluA1, GRIA1, GLUH1, GLUR1
Background: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
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ID gène
- 2890
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Pathways
- Signalisation PI3K-Akt
Antigène
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