FKBP11 anticorps (AA 121-201) (Cy7)

N° du produit ABIN1708257

Cet anticorps anti-FKBP11 est un anticorps Lapin Polyclonal détectant FKBP11 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour FKBP11 anticorps (AA 121-201) (Cy7) (ABIN1708257)

Antigène: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FKBP11 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FKBP11 anticorps (Cy7)

Épitope: AA 121-201

Homologie: Human,Mouse,Rat,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FKBP11

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FKBP11

Antigène: FKBP11 (FK506 Binding Protein 11, 19 KDa (FKBP11))

Autre désignation: FKBP11

Sujet:

Synonyms: 19 kDa FK506 binding protein, 19 kDa FK506-binding protein, 19 kDa FKBP, FK506 binding protein 11 19 kDa, FK506 binding protein 11, FK506-binding protein 11, FKB11_HUMAN, FKBP 19, FKBP-11, FKBP-19, Fkbp11, FKBP19, MGC54182, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP11, PPIase, PPIase FKBP11, Rotamase.

Background: The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP11 (FK506-binding protein 11), also known as FKBP19 or peptidyl-prolyl cis-trans isomerase FKBP11, is a 201 amino acid single-pass membrane protein belonging to the FKBP-type PPIase family, a group of proteins known to catalyze the folding of proline-containing polypeptides. Containing one PPIase FKBP-type domain, FKBP11 is expressed in secretory tissues such as pancreas, pituitary, stomach, lymph node and salivary gland, and is encoded by a gene that maps to human chromosome 12q13.12. FK506 and rapamycin are known to inhibit FKBP11?s peptidyl-prolyl isomerase activity.

ID gène: 51303