GOT1L1 anticorps (AA 201-300) (Cy7)

N° du produit ABIN1708923

Cet anticorps anti-GOT1L1 est un anticorps Lapin Polyclonal détectant GOT1L1 dans WB, IF (cc) et IF (p). Adapté pour Souris et Rat.

Aperçu rapide pour GOT1L1 anticorps (AA 201-300) (Cy7) (ABIN1708923)

Antigène: GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GOT1L1 est conjugé à/à la Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-GOT1L1 anticorps (Cy7)

Épitope: AA 201-300

Réactivité croisée: Souris, Rat

Homologie: Human,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GOT1L1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GOT1L1

Antigène: GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))

Autre désignation: GOT1L1

Sujet:

Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.

Background: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

ID gène: 137362